UV-Induced Photodegradation of 2-Aminothiazole-4-Carboxylic Acid: Identification of New Carbodiimide Molecules.

ABSTRACT: The UV-induced photolysis of 2-aminothiazole-4-carboxylic acid (ACA), a biologically active molecule, was studied using the infrared matrix isolation method. As the first step of photolysis, a decarboxylation reaction occurred. Subsequently, two main photolysis pathways of 2-aminothiazole were observed, during which a number of new molecules, including potential prebiotic carbodiimides or molecular complexes, were identified. The CS-CN bond cleavage path produced N-(1-sulfanylethen-2-yl)carbodiimide (fp1), N-(thiiran-2-yl)carbodiimide (fp3), N-(1-thioethan-2-yl)carbodiimide (fp2), N-(1-thioethan-1-yl)carbodiimide (fp4) and N-(1-thioethan-2-yl)cyanamide (fp33), which were identified for the first time. In this channel, additional disruption of the N-C bond

SUBMITTER: Bumaznik D 

PROVIDER: S-EPMC12472919 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature