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Quantification of hounsfield unit difference in heterogeneous hematoma predicts poor functional outcomes in acute intracerebral hemorrhage.


ABSTRACT:

SUBMITTER: Wu Q 

PROVIDER: S-EPMC12475111 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature

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Quantification of hounsfield unit difference in heterogeneous hematoma predicts poor functional outcomes in acute intracerebral hemorrhage.

Wu Qian Q   Huang Lei L   Chen Na N   Ren Siying S   Ye Fei F   Zhao Xu X   Wu Guofeng G   Wang Likun L  

Scientific reports 20250926 1


Heterogeneous hematoma exhibiting a blend sign undergo dynamic changes associated with neurological injury. This study quantified hyperdense and hypodense regions of blend sign on serial non-contrast computed tomography (NCCT) using ITK-SNAP, calculated the mean hounsfield unit (HU) difference (dHU), and evaluated its prognostic value in 261 patients with intracerebral hemorrhage (ICH). All patients underwent baseline CT within 6 h of symptom onset and follow-up CT within 24 h. Logistic regressi  ...[more]

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