Reviewing the lines of therapy-concept in cancer treatment: a survey study among physicians.

ABSTRACT:

Background

While the line of therapy (LOT) concept is crucial for clinical decision-making in oncology, the concept lacks a consensual understanding bearing the risk of miscommunication. This study examines physicians' understanding of LOT, its perceived relevance, and the events and actions that determine a change of LOT within German oncological networks.

Methods

Employing a snowball sampling approach, an anonymous online-administered survey was conducted among German physicians with oncological experience. Descriptive statistics and consensus metrics (Gini Mean Difference [GMD] and normalized entropy) were used to summarize the survey results and the relative agreement among the respondents, respectively.

Results

Sixty physicians completed the survey. The majority

SUBMITTER: Falchetto LMM 

PROVIDER: S-EPMC12482237 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature