Predictors of quality of life in multiple myeloma patients: a multi-centered cross-sectional study.

ABSTRACT:

Background

Multiple myeloma (MM) substantially impairs health-related quality of life (QoL). Evidence from low- and middle-income countries is limited, and identifying reliable predictors of QoL is essential to guide supportive care strategies.

Methods

We conducted a multicenter cross-sectional study of 202 MM patients from six hospitals in the West Bank, Palestine (2018-2025). Patients completed the validated Arabic EORTC QLQ-MY20 questionnaire. Clinical, demographic, and therapeutic variables were collected, and predictors of QoL subscales were analyzed using non-parametric tests and multivariable linear regression with LASSO variable selection.

Results

In the Side Effects of Treatment subscale, abdominal pain (β = 6.75; 95% CI: 1.92-11.59; p = 0.006), chest pain (β

SUBMITTER: Abu Hamdeh N 

PROVIDER: S-EPMC12487296 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature