Use of isavuconazole in critically ill patients in intensive care units: a prospective, observational, multicentre, cohort study.

ABSTRACT:

Objectives

In this multicentre, prospective study, we aimed to describe the use of isavuconazole in critically ill adult patients in ICU, in terms of patient characteristics, infection characteristics and outcomes.

Methods

Prospective, observational study of ICU patients treated with isavuconazole from January 2023 to 30 April 2025 in 17 centres (ISA-SITA study within the MULTI-SITA project).

Results

A total of 177 ICU patients treated with isavuconazole were included in the study. Most patients showed at least one European Organisation for Research and Treatment of Cancer/Mycoses Study Group Education and Research Consortium (EORTC/MSGERC) or FUNgal Diseases in adult patients in Intensive Care Unit (FUNDICU) host factor (141/177, 79.7%). Overall, 82/177 patients (46.

SUBMITTER: Giacobbe DR 

PROVIDER: S-EPMC12498522 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature