Does e-cigarette nicotine strength influence substitution for combustible cigarettes?

ABSTRACT: Using the Experimental Tobacco Marketplace, we examined the effects of e-liquid freebase nicotine strength (3-24 mg/mL) and e-liquid price (US$0.25-$1.00/mL) on behavioral economic substitution for cigarettes in dual cigarette/e-cigarette (n = 41) and exclusive cigarette (n = 40) users. Subjective effects of nicotine strength were also examined. All nicotine strengths served as a substitute for combustible cigarettes, with greater substitution observed in dual users. When analyzing e-liquid volume purchased (mL), nicotine strength did not influence substitution; however, when analyzing e-liquid nicotine purchased (mg), degree of substitution increased as a function of nicotine strength. Additionally, higher nicotine strengths reduced the volume and probability of e-liquid purchasing, incre

SUBMITTER: Stein JS 

PROVIDER: S-EPMC12503084 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature