A Case Report of Laparoscopic Distal Gastrectomy for Gastric Cancer with Autosomal Dominant Polycystic Kidney Disease and Multiple Liver Cysts.

ABSTRACT:

Introduction

Here, we report a case of gastric cancer associated with autosomal dominant polycystic kidney disease (ADPKD).

Case presentation

A 73-year-old woman with chronic renal failure due to polycystic kidneys, who was undergoing hemodialysis treatment three times a week for 1 month, was admitted to our hospital because of anemia. She reported that her mother had suffered from polycystic kidney disease. Gastrointestinal fiberscopy revealed a type 1 cancerous lesion in the lesser curvature of the antrum. Histopathological analysis of gastric tumor biopsy specimens revealed differentiated tubular adenocarcinoma. Abdominal computed tomography revealed multiple cysts in the liver, cystic lesions on both kidneys, and thickening of the gastric wall. A laparoscopic distal gastrectomy with lymph node dissection was performed.

Conclusion

Reports of the association between gastric cancer and ADPKD are exceptionally uncommon. Especially, no cases of laparoscopic distal gastrectomy for gastric cancer with ADPKD have been previously reported. To our knowledge, this is the first report of laparoscopic surgery for gastric cancer with ADPKD and multiple liver cysts.

SUBMITTER: Kato Y 

PROVIDER: S-EPMC12503541 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature