Red blood cell transfusion practice and cardiac comorbidities in patients with myelodysplastic syndromes.

ABSTRACT:

Background

Evidence guiding optimal transfusion practice for patients with myelodysplastic syndromes (MDS) is lacking. Many patients have concurrent cardiac disease. Data on practice are sparse. We aimed to describe the use of red blood cell (RBC) transfusion and the prevalence of cardiac comorbidities in patients with MDS within Australia's largest public hospital network to better understand real-world practices and outcomes.

Methods

We conducted a retrospective cohort study of patients aged ≥18 years with MDS, MDS/myeloproliferative overlap neoplasm or chronic myelomonocytic leukemia admitted from 2016 to 2018 to determine RBC transfusion-related endpoints.

Results

One hundred and seventy-nine patients (median age 78 years, 61.5% male) were included, with a median

SUBMITTER: Mo A 

PROVIDER: S-EPMC12531908 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature