Transcriptomic and physiological analyses revealed nicotianamine enhances wheat tolerance to excess manganese.

ABSTRACT: Manganese (Mn) is an essential plant micronutrient but toxic at supra-optimal concentrations. Although nicotianamine (NA) biosynthesis is metal inducible, its specific role in Mn detoxification in wheat remains poorly characterized. Integrated transcriptomic and physiological analyses of Mn-tolerant (ET8, Carazinho) and Mn-sensitive (ES8, Egret) wheat near-isogenic lines and their parental cultivars under excess Mn revealed pronounced upregulation of genes encoding nicotianamine synthase (TaNAS), nicotianamine aminotransferase (TaNAAT), and putative Mn-NA transporters (TaYSL2, TaYSL6) in tolerant genotypes. This transcriptional response correlated with elevated NA accumulation in roots under Mn stress. Exogenous NA application enhanced Mn tolerance in hydroponic

SUBMITTER: Luo D 

PROVIDER: S-EPMC12554150 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature