Validation of the FACIT-Fatigue scale in patients with locally advanced or metastatic breast cancer.

ABSTRACT:

Background

Cancer-related fatigue (CRF) is a common symptom in patients with locally advanced or metastatic breast cancer (LA/M BC) receiving taxane-based chemotherapy (CT). CRF is commonly assessed as a subjective experience by patient questionnaires, such as the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue. The aim of this study was to extend the validity of the FACIT-Fatigue and estimate clinically meaningful group-level differences in this patient population.

Materials and methods

This was a prospective, noninterventional, multinational study conducted in the United States and Italy from October 2021 to August 2023 in adult patients with LA/M BC eligible to receive cycle 1 of taxane-based CT. Patients completed a FACIT-Fatigue survey before starting C

SUBMITTER: Fabi A 

PROVIDER: S-EPMC12573256 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature