Information-Theoretic Trigger Surprisal and Future Headache Activity.

ABSTRACT:

Importance

Identifying migraine triggers is a common goal for individuals with migraine but remains challenging due to the vast number of possible triggers and their fluctuating nature. A measurement system quantified through information-theoretic surprisal (ie, the negative logarithm of the probability of an observed exposure) could be valuable for evaluating the wide range of possible triggers for future migraine attacks.

Objective

To evaluate the association between surprisal and future headache attacks.

Design, setting, and participants

This cohort study conducted from April 2021 to December 2024 included 109 participants with migraine who completed diary entries of potential migraine triggers and migraine attacks within 12 and 24 hours after trigger exposure twic

SUBMITTER: Turner DP 

PROVIDER: S-EPMC12606372 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature