Serodiagnosis of amoebic abscess: a retrospective diagnostic accuracy study of kits marketed in Europe.

ABSTRACT: Amoebiasis is a cosmopolitan parasitic disease caused by Entamoeba histolytica. The most lethal form is extra-intestinal amoebiasis, mainly manifesting as liver abscesses. Diagnosis is based on clinical, radiological, and biological tests. However, there are currently few serology reagents still available on the European market for in vitro diagnosis, and comparative studies of existing reagents are required. We evaluated the performances of the four currently available reagents, either as standalone tests or in combination. Two enzyme-linked immunosorbent assays (ELISAs) for the detection of E. histolytica IgG were assessed: one manufactured by Bordier and the other by NovaTec. Additionally, an indirect hemagglutination technique, ELI.H.A Amoeba, and a latex pa

SUBMITTER: Pretot E 

PROVIDER: S-EPMC12607903 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature