Diverse bacteriohemerythrin genes of <i>Methylomonas denitrificans</i> FJG1 provide insight into the survival and activity of methanotrophs in low oxygen ecosystems.

ABSTRACT: Proteobacterial methanotrophs are dependent on the oxidation of methane for ATP production and assimilation of carbon into biomass. Interestingly, some types of gammaproteobacterial methanotrophs thrive in oxygen-depleted zones of lakes and other aquatic ecosystems despite their reliance on oxygen to support methane oxidation. The model gammaproteobacterial methanotroph, Methylomonas denitrificans FJG1, oxidizes methane coupled to nitrate reduction under hypoxia and highly upregulates its expression of bacteriohemerythrin (Bhr). Bhr is a homolog of eukaryotic hemerythrin, which is a protein associated with oxygen binding. Ten bhr homologs were identified in the genome of M. denitrificans FJG1, requiring phylogenetic and gene expression analyses to pinpoint which homolo

SUBMITTER: Weiblen C 

PROVIDER: S-EPMC12607906 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature