Phenotypic and genomic characterization of Paenibacillus salivarius sp. nov., isolated from the human oral cavity.

ABSTRACT: A novel Gram-stain-negative, facultatively anaerobic, endospore-forming bacterium, designated DYY-L-2^T, was isolated from the saliva of a 69-year-old patient with chronic periodontitis in Hengyang, China. Phylogenetic analysis based on the 16S rRNA gene sequences revealed that strain DYY-L-2^T belonged to the genus Paenibacillus, with the highest similarity to Paenibacillus konsidensis LBY^T (98.6%), followed by Paenibacillus vini LAM0504^T (97.2%). Whole-genome sequencing yielded a complete circular chromosome of 5,642,305 bp with a genomic DNA G + C content of 50.8%. Overall genome relatedness index analysis indicated low average nucleotide identity (ANI < 80%) and in silico DNA-DNA hybridization (isDDH < 25%) values between strain DYY-L-2^T</

SUBMITTER: Huang X 

PROVIDER: S-EPMC12613345 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature