Transition from HIV post-exposure prophylaxis to pre-exposure prophylaxis and awareness-to-use cascade among men who have sex with men: a longitudinal study in Guangxi, China.

ABSTRACT:

Background

HIV post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP) are effective yet underutilized HIV prevention modalities. This study aims to evaluate the awareness-to-use cascade for PEP and PrEP, and to examine the transition from PEP to PrEP among men who have sex with men (MSM). We will discuss the rationale for using PrEP after PEP use.

Methods

With an observational, longitudinal study design, MSM were recruited from five cities in Guangxi, China. Participants completed questionnaires every 3 months and were tracked for 12 months. Descriptive statistics summarized the awareness, use, cascade and transition of PEP and PrEP. The effect of PEP use on PrEP use was analyzed using Generalized Estimating Equations.

Results

A total of 363 eligible MSM

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC12625293 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature