Odorant Receptor <i>OR45a</i> Mediates Female-Specific Attraction to <i>cis</i>-Linalool Oxide in <i>Bactrocera dorsalis</i>.

ABSTRACT: Bactrocera dorsalis Hendel is a devastating invasive pest that costs billions of dollars in agricultural losses worldwide. Current control strategies rely heavily on male-specific attractants such as methyl eugenol, which are less effective against females, underscoring the need for female-targeted control approaches. Here, we investigated the molecular mechanisms underlying female attraction to cis-linalool oxide by functionally characterizing the odorant receptor OR45a, identifying it as a molecular target for female-oriented pest management. We conducted spatiotemporal expression analysis of OR45a in response to cis-linalool oxide, followed by RNAi and behavioral assays. Phylogenetic analysis of OR45a orthologs from 10 Dipteran species, combined with structural topo

SUBMITTER: Liang B 

PROVIDER: S-EPMC12653480 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature