Investigating in-hospital transmission of <i>Clostridioides difficile</i> from asymptomatic patients.

ABSTRACT:

Background

Clostridioides difficile is a bacillus that can colonize the intestinal tract. C. difficile infection (CDI) is a common, health care-associated disease often coinciding with antibiotic use, with presentation ranging from diarrhea to toxic megacolon and death. However, individuals can carry the pathogen without exhibiting symptoms of disease. C. difficile carriers may serve as an important reservoir for in-hospital transmission of C. difficile. The objective of this study was to assess the role asymptomatic C. difficile carriers may play in pathogen transmission.

Methods

In this retrospective cohort study, rectal swabs collected to test for antimicrobial-resistant organisms either upon admission or during the hospital stay were us

SUBMITTER: Baker SJC 

PROVIDER: S-EPMC12657012 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature