Solvent-mediated chirality inversion in orthogonal hierarchical assembly of achiral carbene-anchored gold cluster.

ABSTRACT: Precisely constructing homochiral helical nanostructures from achiral molecules by non-covalent interactions remains challenging owing to the untraceable handedness control at different hierarchical levels. Here, we present an aurophilicity-assisted orthogonal assembly strategy, enabling not only the homochiral assembly of an achiral carbene-anchored trinuclear gold cluster with chiral amines but also the inversion of circularly polarized luminescence (CPL). This gold cluster could spontaneously form random right- or left-handed helices, while introduction of chiral amines effectively drives the formation of hierarchically homochiral twists with |g_lum| of 10^-2, directed by inherent aurophilicity of gold cluster and orthogonal intermolecular C-H⋅⋅⋅O/N interactions. Fur

SUBMITTER: Liu YJ 

PROVIDER: S-EPMC12657935 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature