Combined magnetic resonance imaging with serum CA125 for dysmenorrhea in adenomyosis.

ABSTRACT: To evaluate the synergistic predictive capacity of MRI lesion classification and serum CA125 for symptom manifestation (dysmenorrhea/menorrhagia) and explore associated adenomyosis pathogenesis. Patients before focused ultrasound ablation surgery were categorized into MRI-based severity group (Group A) and MRI-based non-severity group (Group B). Binary logistic regression was employed to identify the factors associating dysmenorrhea and CA125 level in total cohort and subgroups via MRI-based classifications criteria. The receiver-operating characteristic (ROC) curve was applied to assess the utility of CA125 for dysmenorrhea. Patients in dysmenorrhea subtype exhibited higher CA125 levels compared with those in non-dysmenorrhea subtype in total cohort and Group A (P < 0.05). Uterine volumes

SUBMITTER: Su B 

PROVIDER: S-EPMC12660971 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature