Systematic literature review and meta-analysis on the reproductive effects of micro- pollutants in humans and animals.

ABSTRACT:

Background

Micro-pollutants, such as particulate matter, heavy metals, endocrine-disrupting compounds, and persistent organic pollutants, raise significant concerns regarding reproductive health in both humans and animals.

Methods

This systematic review and meta-analysis, conducted according to PRISMA guidelines, assessed available evidence on micro-pollutant exposure and reproductive outcomes. Out of 2,134 records identified, 52 studies (31 human, 21 animal) met inclusion criteria.

Results

Exposure to micro-pollutants was consistently associated with adverse reproductive outcomes. Human studies reported increased risks of irregular menstruation, preterm delivery (OR = 1.42), intrauterine growth restriction (OR = 1.36), and reductions in sperm concentration (SMD = -0.

SUBMITTER: Coppeta L 

PROVIDER: S-EPMC12673271 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature