The Taiwan Precision Medicine Initiative provides a cohort for large-scale studies.

ABSTRACT: Han Chinese people comprise nearly 20% of the global population but remain under-represented in genetic studies^1,2, so there is an urgent need for large-scale cohorts to advance precision medicine. Here we present the Taiwan Precision Medicine Initiative (TPMI), established by Academia Sinica in collaboration with 16 major medical centres around Taiwan, which has recruited 565,390 participants who consent to provide DNA samples for genetic profiling and grant access to their electronic medical records (EMRs) for research. EMR access is both retrospective and prospective, allowing longitudinal studies. Genetic profiling is done with population-optimized arrays of single-nucleotide polymorphisms for people of Han Chinese ancestry, which enable genome-wide association^3,4

SUBMITTER: Yang HC 

PROVIDER: S-EPMC12675286 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature