How I do it: sequential robot-assisted stereotactic biopsy and laser interstitial thermal therapy for epilepsy associated with brain tumors.

ABSTRACT:

Background

Laser Interstitial Thermal Therapy (LITT) is a minimally invasive option for treating epilepsy and neuro-oncologic lesions, including those deemed inoperable. However, it does not allow for histomolecular diagnosis.

Methods

We describe our technique for combining stereotactic brain biopsy and LITT, focusing on biopsy sample quantity and its effects on MRI thermometry and ablation quality.

Conclusion

Stereotactic biopsy can be safely integrated with LITT. Limiting sampling to two specimens minimizes air diffusion and hemorrhagic risk, reducing thermometric artifacts and preserving the accuracy of ablation.

SUBMITTER: Aboubakr O 

PROVIDER: S-EPMC12678548 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature