Identification of Bitter Peptides in <i>Lilium lancifolium</i> Thunb.; Peptidomics, Computational Simulation and Cellular Functional Assays.

ABSTRACT: Lilium lancifolium Thunb., as a predominant variety of medicinal and edible lilies, has long been renowned in traditional medicine for "moistening the lungs, relieving coughs, and calming the mind to soothe the heart." The bitter taste formation in L. lancifolium is predominantly attributed to secondary metabolites such as alkaloids, this study explores an alternative mechanism underlying taste divergence among Lilium brownii var. viridulum, and Lilium pumilum DC, proposing a foundational scientific question: Are peptides one of the important sources of bitterness in Lilium lancifolium Thunb.? Peptidomic analysis identified 8479 peptide sequences, with 46.27% upregulated in L. lancifolium flesh. Through high-throughput molecular docking with

SUBMITTER: Dong Z 

PROVIDER: S-EPMC12692226 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature