Postprandial 2-h glucose tolerance is associated with diabetes diagnosis, diabetes mortality, and cardiovascular mortality.

ABSTRACT: Postprandial plasma glucose between 4 and 7.9 h is associated with the diagnosis of diabetes, diabetes mortality, and cardiovascular mortality. However, it is unknown whether 2-hour plasma glucose during the oral glucose tolerance test conducted in this postprandial period (4-7.9 h), termed as 2-h PG_{OGTT@4-7.9 h}, can accurately classify diabetes diagnosis and predict mortality risks. This study aimed to address these questions using 2,347 adult participants. Diabetes was defined as HbA_1c ≥ 6.5%, and the ability of 2-h PG_{OGTT@4-7.9 h} to classify diabetes was analyzed using receiver operating characteristic curves. Cox proportional hazards models were employed to estimate mortality hazard ratios (HRs) and 95% confidence intervals (CIs). The results showed tha

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12705769 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature