Perceptions of persons deprived of liberty regarding tuberculosis vaccine research.

ABSTRACT: Several tuberculosis (TB) vaccine candidates are currently advancing to late-stage clinical trials. Prisons in low-and middle-income countries harbor some of the highest rates of TB in the world, making persons deprived of liberty (PDL) an important population to prioritize for the introduction of effective vaccines. However, the inclusion in clinical trials raises significant ethical concerns due to a history of exploitation and mistreatment within medical research. To date, PDL own perspectives on participating in vaccine research have been largely overlooked. This multicenter qualitative study employed focus group (FG) discussions in seven state prisons across four of the five regions of Brazil, involving 91 incarcerated individuals (64 men and 27 female) between February and August 202

SUBMITTER: Pires MCCF 

PROVIDER: S-EPMC12707645 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature