Consistency of Blood Pressure Response to Potassium-Enriched Salt in the China Salt Substitute Study.

ABSTRACT:

Background

Large between-person differences in blood pressure (BP) responses to sodium reduction, potassium supplementation, and potassium-enriched salt have been suggested by prior studies. However, limitations in research designs and misinterpretation of findings mean that overestimation of true between-person variation in response is likely.

Methods

Systolic BP (SBP) response during a 4-week run-in period on potassium-enriched salt was measured for 608 individuals. Participants were defined as apparently sensitive if SBP fell and apparently resistant if SBP was unchanged or rose. The effect of potassium-enriched salt compared with regular salt on SBP was then compared for apparently sensitive versus apparently resistant groups over a subsequent 12-month postrandomization

SUBMITTER: Kissock K 

PROVIDER: S-EPMC12711297 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature