SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management.

ABSTRACT:

Background

Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. Selection and retrieval of an optimal SNP set from publicly available databases have emerged as the foremost bottlenecks in designing large-scale linkage disequilibrium studies, particularly in case-control settings.

Results

We describe the architectural structure and implementations of a novel software program, SNPHunter, which allows for both ad hoc-mode and batch-mode SNP search, automatic SNP filtering, and retrieval of SNP data, including physical position, function class, flanking sequences at user-defined lengths, and heterozygosity from NCBI dbSNP. The SNP data extracted from dbSNP via SNPHunt

SUBMITTER: Wang L 

PROVIDER: S-EPMC1274256 | biostudies-literature | 2005 Mar

REPOSITORIES: biostudies-literature