High colonization by multidrug-resistant and virulent Staphylococcus aureus genotypes among critically ill patients in the COVID-19 pandemic in a Brazilian hospital.

ABSTRACT:

Background

The COVID-19 pandemic has dramatically impacted in patients from Intensive Care Units (ICUs), making them more vulnerable to infection/colonization by clinically relevant pathogens. However, little is known about the Staphylococcus aureus isolates that colonized these patients during the pandemic.

Methods

Consecutive S. aureus isolates from surveillance swabs of patients of two ICUs of a hospital in Rio de Janeiro, between September 2020 and September 2021, were evaluated for phenotypic antimicrobial resistance. Methicillin-resistant S. aureus (MRSA) isolates were evaluated for resistance and virulence genes, biofilm production, and their genotypic profiles. Medical records were accessed for clinical and demographic data.

Results

Among 255 patients colonize

SUBMITTER: De Oliveira TLR 

PROVIDER: S-EPMC12751815 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature