Expression of hemerythrin-like genes from the obligate aerobe <i>Myxococcus xanthus</i> improves the growth of the industrially relevant <i>Gluconobacter oxydans</i>.

ABSTRACT: Myxococcus xanthus is a ubiquitous, obligately aerobic soil bacterium. M. xanthus has many two-component systems that serve to regulate responses to environmental stimuli. One of these systems, the multicomponent signaling system named the NmpRSTU pathway has been demonstrated to regulate genes that are predicted to be important for oxygen utilization, including the gene mxan_5531, which encodes a predicted hemerythrin-like protein. The family of proteins that includes hemerythrin-like proteins binds oxygen coordinated by a di-iron cofactor. Based on the sequence alignments and predictive structural analysis, we have determined that M. xanthus encodes at least five other predicted hemerythrin-like proteins. Of these six proteins predicted to be hemerythrin-like

SUBMITTER: Fleegal AL 

PROVIDER: S-EPMC12753109 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature