Autoimmune glial fibrillary acid protein astrocytopathy initially misdiagnosed as tuberculous meningitis: a case report.

ABSTRACT:

Background

Autoimmune glial fibrillary acid protein astrocytopathy is an autoimmune central nervous system disorder that affects the nervous system. The clinical presentation is heterogeneous. The specific diagnostic marker of autoimmune glial fibrillary acid protein astrocytopathy is the presence of glial fibrillary acid protein antibodies. However, standardized diagnostic and therapeutic criteria are currently lacking, especially because its early clinical symptoms are similar to those of tuberculous meningitis, which leads to a high risk of misdiagnosis and delayed treatment in clinical practice.

Case presentation

We present two cases of autoimmune glial fibrillary acid protein astrocytopathy that were initially misdiagnosed as tuberculous meningitis. The first case is a

SUBMITTER: Li L 

PROVIDER: S-EPMC12797936 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature