Risk Factors and Outcomes of Reintubation Following Combined Heart-Lung Transplantation.

ABSTRACT:

Background

Unplanned reintubation after combined heart-lung transplantation (HLT) significantly affects morbidity and mortality, yet national data are limited. We evaluated the incidence, predictors, timing, and outcomes associated with reintubation after HLT.

Methods

We retrospectively reviewed adults undergoing primary HLT in the UNOS registry from January 2004 to September 2024. Patients were stratified by reintubation status (defined as re-established mechanical ventilation (MV) after initial extubation). Propensity matching (1:1) balanced recipient and donor characteristics. Multivariable logistic regression models identified independent risk factors.

Results

Among 609 adult HLT recipients, 165 (27.1%) required postoperative reintubation. After 1:1 propensity sco

SUBMITTER: Kwon YIC 

PROVIDER: S-EPMC12801093 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature