Medication adherence in patients with acutely decompensated heart failure: A cross-sectional study in the emergency department (ADHF-ED).

ABSTRACT:

Aims

Non-adherence to guideline-directed medical therapy may worsen outcomes in chronic heart failure (CHF). Objectively assessed adherence in patients presenting with acutely decompensated heart failure (ADHF) remains largely unexplored. This study evaluated adherence to medication in patients with ADHF presenting in the emergency department.

Methods and results

This cross-sectional study assessed medication adherence using both indirect (self-reported) and direct methods (qualitative toxicological analysis in urine). A total of 100 patients were included of whom 61% were men, with a mean age of 77.9 ± 10.1 years, and a median N-terminal pro-B-type natriuretic peptide level of 4846 pg/ml. In 39% of patients, all prescribed CHF medications were detected in urine, indicating

SUBMITTER: Kunz M 

PROVIDER: S-EPMC12803543 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature