Development and Validation of a Magnetic Resonance Imaging-Guided Adaptive Radiotherapy Workflow for Long, Continuous Planning Target Volumes.

ABSTRACT: IntroductionOwing to the limitation in the field size of the magnetic resonance (MR)-Linac, currently, tumors with a length of >20 cm cannot be treated. Thus, the present study aimed to develop an expanded magnetic resonance imaging-guided adaptive radiotherapy (MRIgART) workflow for long, continuous planning target volumes (PTVs).MethodsThe PTVs were divided into two sub_target volumes (PTV_sub1 and PTV_sub2). We established two isocenters and defined a field overlap region. By adjusting the MR scan range, devising the online and offline adaptive procedures, synchronizing the online adaptive processes, and constructing a pretreatment dose evaluation, a new MRIgART workflow for long PTVs was established. The new workflow was validated using an in-house-made MR phantom. Additionally, the Ar

SUBMITTER: Yan L 

PROVIDER: S-EPMC12816554 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature