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ABSTRACT: Background
Axial spondyloarthritis (axSpA) is a chronic autoinflammatory disease with heterogeneous clinical features, presenting considerable complexity for sustained patient self-management. Although the use of large language models (LLMs) in health care is rapidly expanding, there has been no rigorous assessment of their capacity to provide axSpA-specific health guidance.Objective
This study aimed to develop a patient-centered needs assessment tool and conduct a systematic evaluation of the quality of LLM-generated health advice for patients with axSpA.Methods
A 2-round Delphi consensus process guided the design of the questionnaire, which was subsequently administered to 84 patients with axSpA and 26 rheumatologists. Patient-identified key concerns were formulat
SUBMITTER: Bai J
PROVIDER: S-EPMC12824573 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature