Differences in benefits of office based opioid treatment: Secondary analyses across sub-groups in the PROUD randomized controlled implementation trial.

ABSTRACT:

Background and aims

Female, Hispanic, and Black patients with opioid use disorder (OUD) are less likely to receive OUD medication treatment than other patients. The PROUD (PRimary care Opioid Use Disorders treatment) trial demonstrated that implementation of primary care (PC) nurse care management increases OUD medication treatment compared with usual care (UC). This study assessed whether the PROUD intervention's effect differed across sex, race and ethnicity.

Design

Secondary analyses of cluster-randomized implementation trial.

Setting

12 PC clinics (2 per health system) in five states in the USA, randomized to UC or intervention, stratified by health system.

Participants

PC patients 16-90 years old.

Intervention

Three strategies to implement office-ba

SUBMITTER: Bradley KA 

PROVIDER: S-EPMC12829311 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature