Tailored Kidney Stone Prevention Improves Metabolic Risk Factors and Reduces Renal Colic Rate.

ABSTRACT:

Introduction

There is limited real-world data on the effectiveness of combined prophylactic measures to prevent recurrent kidney stone formation.

Methods

This single-center retrospective study evaluated the effect of combined, patient-tailored prophylaxis on metabolic risk factors, urinary crystallization risk indices, and renal colic and urological intervention rates in a real-life clinical setting.

Results

Four hundred ninety patients with nephrolithiasis (NL) with a median follow-up of 12.8 months were evaluated. After the introduction of prophylaxis, the main metabolic risk factors, namely urinary volume, oxalate, calcium, and citrate excretion improved significantly in patients presenting the specific risk factor at baseline (+ 653 ml/24 h for urinary volume, - 1

SUBMITTER: Van de Perre E 

PROVIDER: S-EPMC12830155 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature