Peptide-conjugated biodegradable polyester scaffolds for bone regeneration.

ABSTRACT: Bone grafting remains one of the most common surgical procedures worldwide, with alloplastic grafts offering scalable and versatile alternatives to autografts. Biodegradable polyester-based scaffolds have emerged as a promising solution due to their tunable mechanical properties, biocompatibility, biodegradability, and recent advances in fabrication technologies. However, their lack of intrinsic bioactivity has driven increasing interest in bioactive functionalization. As a candidate for such functionalization, peptides offer several advantages, including ease of synthesis, specificity in biological interactions, and adaptability to chemical modification. This review provides a comprehensive overview of biodegradable polyester-peptide scaffold systems for bone tissue engineering. In partic

SUBMITTER: Zhou T 

PROVIDER: S-EPMC12834038 | biostudies-literature | 2026 Jun

REPOSITORIES: biostudies-literature