Alzheimer's clinical research data via R packages: The alzverse.

ABSTRACT:

Introduction

Sharing clinical research data is essential for advancing Alzheimer's disease (AD) research, yet challenges in accessibility, standardization, documentation, usability, and reproducibility persist.

Methods

We developed R data packages to streamline access to curated datasets from key AD studies. A4LEARN includes data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) randomized trial and its companion observational study, the Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN). ADNIMERGE2 contains curated data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), a longitudinal biomarker and imaging study.

Results

These packages bundle data, documentation, and reproducible analysis vignettes into portable, analysis-r

SUBMITTER: Donohue MC 

PROVIDER: S-EPMC12854935 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature