Universal Newborn Screening for Congenital Cytomegalovirus Using Dried Blood Spot Specimens.

ABSTRACT:

Importance

Congenital cytomegalovirus (cCMV) is the most common nongenetic cause of sensorineural hearing loss in children and a cause of long-term neurological disabilities. In the absence of universal screening, cCMV disease in many newborns will go undiagnosed and untreated.

Objective

To determine the feasibility, screen-positive rate, and parental acceptance of newborn screening for cCMV using dried blood spot (DBS) specimens.

Design, setting, and participants

In this population-based diagnostic study, newborns whose DBS specimens were submitted to the New York State Newborn Screening Program from October 2, 2023, through September 30, 2024, for routine screening were also screened for CMV. Parents were given the option to opt out of receiving CMV results. Infecti

SUBMITTER: Tavakoli NP 

PROVIDER: S-EPMC12856680 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature