Assessing small-lesion detectability and acquisition time optimisation in silicon-detector-Based PET: a phantom study.

ABSTRACT:

Background

The adoption of silicon photomultiplier (SiPM) detectors over conventional photomultiplier tubes (PMTs) in Positron Emission Tomography (PET) has enhanced overall system performance. In this phantom study, small-lesion detectability was assessed for SiPM-based and PMT-based PET systems for various inhomogeneity sizes, acquisition times and activity contrasts between the inhomogeneity and background.

Methods

Six spheres of internal diameters ranging between 4.0 mm and 13.0 mm were integrated into a NEMA/IEC PET Body Phantom and filled with fluorodeoxyglucose, with a sphere activity concentration of 29.2 MBq/L and five sphere-to-background activity concentration ratios between 4 and 20. Scans were performed with an SiPM-based system and a PMT-based PET system for ea

SUBMITTER: Leybourne N 

PROVIDER: S-EPMC12858686 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature