Whole-genome sequencing, phenotypic characterization, and antifungal susceptibility profiles of three Aspergillus hortae clinical isolates from Colombia.

ABSTRACT: The Aspergillus genus comprises fungi that are widely distributed in nature. Several Aspergillus sections are important for recycling organic matter; while the Fumigati section is classically associated with compost, the Terrei section also plays a relevant role in this process. Aspergillus hortae is a species from this section that has been isolated from clinical samples, but its role as a pathogenic agent is unclear. In this study, we analysed three clinical isolates of A. hortae from Colombia, initially misidentified as A. terreus. Morphological characterization at 26 °C and 37 °C confirmed its thermotolerant nature. Whole-genome sequencing enabled accurate species identification and revealed phylogenetic divergence from the reference genome. Antifungal susceptibility testing (EUCAST br

SUBMITTER: Marin-Carvajal S 

PROVIDER: S-EPMC12912593 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature