The "male-female health-survival paradox" in frail patients undergoing hip replacement.

ABSTRACT:

Background

The "male-female health-survival paradox" describes women's longer lifespan despite a greater burden of non-fatal chronic conditions-a phenomenon rarely examined in surgical settings. This study investigated whether this paradox exists in a national cohort of frail patients undergoing hip replacement and explored its underlying mechanisms. We hypothesized that in this cohort: (1) female patients would be less healthy, presenting with a higher prevalence of frailty, older age, and a higher Charlson Comorbidity Index (CCI); and (2) frail men would experience higher in-hospital mortality.

Methods

A retrospective cohort study was conducted using the US National Inpatient Sample (2005-2014) A frailty-defining diagnosis cluster was employed to identify frail individuals

SUBMITTER: Lian Q 

PROVIDER: S-EPMC12914919 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature