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Predictive role of weight-adjusted waist index in diabetic peripheral neuropathy among patients with type 2 diabetes mellitus.


ABSTRACT:

Background

Obesity is a known risk factor for diabetic peripheral neuropathy (DPN), but the relationship between body mass index (BMI) and DPN remains controversial.

Aims

This study explores the relationship between weight-adjusted waist index (WWI) and DPN in Chinese patients with Type 2 Diabetes Mellitus (T2DM), with the goal of establishing WWI as an effective tool for the early detection and risk stratification of DPN.

Methods

A total of 1790 participants were included. The relationships between WWI, BMI, WC, and DPN were analyzed using logistic regression, restricted cubic spline, and subgroup analysis, with ROC-AUC used to assess the diagnostic performance of the obesity indices.

Results

During this cross-sectional study, a total of 895 cases of DPN were

SUBMITTER: Cheng MK 

PROVIDER: S-EPMC12931302 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature

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