Photonic-chemostat engineering for efficient continuous cultivation of cyanobacteria.

ABSTRACT: Optimising continuous phototrophic cultivation remains a major challenge for scalable, energy-efficient cyanobacterial bioprocesses. Here, we combine controlled photophysiology, long-term continuous experimentation, multi-parameter analysis, and batch-derived Monod kinetic modelling to define a precise operational window for Synechocystis sp. PCC 6803 under flat-plate photobioreactor (FP-PBR) illumination. Using a fully calibrated FP-PBR platform, we first quantified intrinsic growth limits (µ _max = 0.081-0.118 day^-1) across low, moderate, and high irradiance regimes, establishing the illumination-driven growth ceilings that constrain downstream continuous operation. Guided by these kinetic boundaries, continuous cultivation demonstrated that productive

SUBMITTER: Rahman MR 

PROVIDER: S-EPMC12933868 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature