GNPS Untargeted GC-MS Metabolomic Analysis of Essential Oils From Duguetia lanceolata and Evaluation of Antimicrobial Activity.

ABSTRACT: In this study, the chemical composition of essential oils (EOs) extracted from leaves of Duguetia lanceolata collected in different seasons (autumn and winter) was analyzed using a GNPS untargeted GC-MS metabolomic approach. EO from autumn leaves (EO-A) contained 80 metabolites (93.8%), with limonene (28.5%), (+)-β-pinene (15.0%), cyclocolorenone (12.8%), 6,9-guaiadiene (3.1%), and 4-carvomenthenol (3.1%) as major constituents. EO from winter leaves (EO-W) comprised 102 compounds (88.0%), dominated by β-bisabolene (16.4%), β-gurjunene (6.4%), β-caryophyllene (4.7%), cyclocolorenone (3.9%), and dihydrocarveol (3.3%). The antimicrobial activity of both EOs was evaluated in vitro using the disk diffusion method against gram-positive and gram-negative bacteria, as well as selected yeast strain

SUBMITTER: Monteiro J 

PROVIDER: S-EPMC12935287 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature