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A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.


ABSTRACT: We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximately 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.

SUBMITTER: Siddiqui AS 

PROVIDER: S-EPMC1311911 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature

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A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells.

Siddiqui Asim S AS   Khattra Jaswinder J   Delaney Allen D AD   Zhao Yongjun Y   Astell Caroline C   Asano Jennifer J   Babakaiff Ryan R   Barber Sarah S   Beland Jaclyn J   Bohacec Slavita S   Brown-John Mabel M   Chand Steve S   Charest David D   Charters Anita M AM   Cullum Rebecca R   Dhalla Noreen N   Featherstone Ruth R   Gerhard Daniela S DS   Hoffman Brad B   Holt Robert A RA   Hou Juan J   Kuo Byron Y-L BY   Lee Lisa L C LL   Lee Stephanie S   Leung Derek D   Ma Kevin K   Matsuo Corey C   Mayo Michael M   McDonald Helen H   Prabhu Anna-liisa AL   Pandoh Pawan P   Riggins Gregory J GJ   de Algara Teresa Ruiz TR   Rupert James L JL   Smailus Duane D   Stott Jeff J   Tsai Miranda M   Varhol Richard R   Vrljicak Pavle P   Wong David D   Wu Mona K MK   Xie Yuan-Yun YY   Yang George G   Zhang Ida I   Hirst Martin M   Jones Steven J M SJ   Helgason Cheryl D CD   Simpson Elizabeth M EM   Hoodless Pamela A PA   Marra Marco A MA  

Proceedings of the National Academy of Sciences of the United States of America 20051213 51


We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximately 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci. ...[more]

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