Genetic structure of Anopheles gambiae populations on islands in northwestern Lake Victoria, Uganda.

ABSTRACT:

Background

Alternative means of malaria control are urgently needed. Evaluating the effectiveness of measures that involve genetic manipulation of vector populations will be facilitated by identifying small, genetically isolated vector populations. The study was designed to use variation in microsatellite markers to look at genetic structure across four Lake Victoria islands and two surrounding mainland populations and for evidence of any restriction to free gene flow.

Methods

Four Islands (from 20-50 km apart) and two surrounding mainland populations (96 km apart) were studied. Samples of indoor resting adult mosquitoes, collected over two consecutive years, were genotyped at microsatellite loci distributed broadly throughout the genome and analysed for genetic structure, e

SUBMITTER: Kayondo JK 

PROVIDER: S-EPMC1327676 | biostudies-literature | 2005 Dec

REPOSITORIES: biostudies-literature