What's in the genome of a filamentous fungus? Analysis of the Neurospora genome sequence.

ABSTRACT: The German Neurospora Genome Project has assembled sequences from ordered cosmid and BAC clones of linkage groups II and V of the genome of Neurospora crassa in 13 and 12 contigs, respectively. Including additional sequences located on other linkage groups a total of 12 Mb were subjected to a manual gene extraction and annotation process. The genome comprises a small number of repetitive elements, a low degree of segmental duplications and very few paralogous genes. The analysis of the 3218 identified open reading frames provides a first overview of the protein equipment of a filamentous fungus. Significantly, N.crassa possesses a large variety of metabolic enzymes including a substantial number of enzymes involved in the degradation of complex substrates as well as secondary metabolism. W

SUBMITTER: Mannhaupt G 

PROVIDER: S-EPMC152809 | biostudies-literature | 2003 Apr

REPOSITORIES: biostudies-literature