A Mutation in the luxS gene influences Listeria monocytogenes biofilm formation.

ABSTRACT: Using a Vibrio harveyi reporter strain, we demonstrated that Listeria monocytogenes secretes a functional autoinducer 2 (AI-2)-like signal. A luxS-deficient mutant produced a denser biofilm and attached to a glass surface 19-fold better than the parent strain. Exogenous AI-2 failed to restore the wild-type phenotype to the mutant. It seems that an intact luxS gene is associated with repression of components required for attachment and biofilm formation.

SUBMITTER: Sela S 

PROVIDER: S-EPMC1538747 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature