Meta-analysis of frusemide to prevent or treat acute renal failure.

ABSTRACT:

Objective

To investigate the potential beneficial and adverse effects of frusemide to prevent or treat acute renal failure in adults.

Design

Meta-analysis of randomised controlled trials.

Data sources

Cochrane controlled trials register (2005 issue 4), Embase, and Medline (1966 to 1 February 2006), without language restrictions.

Review methods

Two reviewers checked the quality of the studies and independently extracted data.

Results

Nine randomised controlled trials totalling 849 patients with or at risk of acute renal failure were included. Outcome measures not significantly different after frusemide treatment were in-hospital mortality (relative risk 1.11, 95% confidence interval 0.92 to 1.33), risk for requiring renal replacement therapy or dialysis (

SUBMITTER: Ho KM 

PROVIDER: S-EPMC1553510 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature